Haemorrhagic diathesis in children associated with vitamin K deficiency.
نویسندگان
چکیده
A haemorrhagic diathesis is described in infants; this is preceded and accompanied by constitutional symptoms such as fever, diarrhoea, vomiting, anorexia, and pallor. These children had a severe coagulation abnormality, due to deficiency of vitamin-K-dependent coagulation factors, and it was corrected by administration of vitamin K. No conclusion could be drawn as to the aetiology of this condition but some possible causes are discussed.
منابع مشابه
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Experimental work during the years 1929 to 1934 established the fact that a haemorrhagic disease observed in chicks was due to deficiency of a fatsoluble dietary factor: in 1935 Dam proposed the nane vitamin K (Koagulations vitamin) for this factor. Dam, Sch0nheyder and Tage-Hansen in 1936 demonstrated a hypoprothrombinaemia which prolonged the clotting time in vitamin-K-deficient chicks, altho...
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ورودعنوان ژورنال:
- Journal of clinical pathology
دوره 20 3 شماره
صفحات -
تاریخ انتشار 1967